Unfortunately, no, you can’t treat your kidney infection at home. However, there are complementary treatments that you can do at home, such as taking OTC pain relievers and drinking lots of water. Learn more from our AFC Urgent Care TN team below! What Is a Kidney Infection? A kidney infection, or pyelonephritis, is a type of urinary tract infection where one or both kidneys become infected. They can be infected by bacteria or a ...