5 Key Differences Between COVID-19 And Strep Throat

January 27, 2024

Woman holding onto her neck because she’s not sure if she has a sore throat from strep throat or from COVID-19

As winter arrives, concerns about sore throats prompt considerations of whether the symptoms indicate COVID-19 or strep throat. While both conditions have certain similarities, understanding which is which is very important. 

AFC Urgent Care Mt. Vernon has created a guide to help you understand the differences between Covid-19 and Strep Throat. 

1. Causes: Viral vs. Bacterial Origins

One fundamental contrast lies in the causative agents. COVID-19 is a viral infection caused by the SARS-CoV-2 virus. In contrast, strep throat is a bacterial infection caused by group A Streptococcus bacteria. Understanding this distinction is essential for appropriate medical interventions.

2. Transmission: Airborne vs. Direct Contact

The modes of transmission also vary significantly. COVID-19 primarily spreads through respiratory droplets when an infected person coughs or sneezes, or by touching contaminated surfaces. On the other hand, strep throat is highly contagious through respiratory droplets and direct contact with an infected person. Recognizing how each illness is transmitted is crucial for implementing preventive measures.

3. Symptoms: Respiratory vs. Throat-Centric

While both conditions may involve a sore throat, their symptom profiles differ. COVID-19 predominantly manifests as a respiratory illness, with symptoms such as coughing, difficulty breathing, shortness of breath, congestion, and loss of smell or taste. In contrast, strep throat's symptoms are more focused on the throat, including a rapid-onset sore throat, pain during swallowing, fever, red and swollen tonsils, and swollen lymph nodes.

4. Testing: Viral Tests vs. Bacterial Tests

Diagnostic tests for COVID-19 typically involve viral tests, such as PCR or rapid antigen tests, aimed at detecting the presence of the SARS-CoV-2 virus. In contrast, diagnosing strep throat often involves a bacterial test, like a rapid strep test (throat swab), to identify group A Streptococcus bacteria. Tailoring the testing approach to the specific nature of each infection is crucial for accurate results.

5. Treatment: Antivirals vs. Antibiotics

Treatment approaches also differ due to the distinct nature of the infections. COVID-19 management focuses on antiviral medications and supportive care. In contrast, strep throat is commonly treated with antibiotics, which target the bacterial infection. Understanding these divergent treatment strategies is vital for effective recovery.

AFC Urgent Care Mt. Vernon offers a comprehensive range of tests 

AFC Urgent Care Mt. Vernon offers many diagnostic tests,  including COVID-19 tests (PCR/Antigen) and a Strep test involving a swab to identify bacterial growth. If your results indicate a strep infection, we can provide effective antibiotic treatment. It's crucial to remember that not all illnesses are related to COVID, and winter often brings various unwanted health challenges.


Our urgent care center is accessible every day of the week. Whether you prefer to schedule an appointment or walk-in, AFC Urgent Care Mt. Vernon Accepts most insurances and is here to provide prompt and reliable healthcare services. Be sure to check out our easy to use online payment system where with just a few clicks you can pay your bill.

About Our Services:

Call (914) 202-4830 for more information about our Mt. Vernon urgent care services.