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Does Mono Cause a Rash?

May 5, 2025

Mononucleosis, commonly called mono, is a viral infection often caused by the Epstein-Barr virus (EBV). One of the key symptoms of mono is fatigue, but it can also lead to a variety of other symptoms, including fever, sore throat, and swollen lymph nodes. A common question among those experiencing mono is whether it causes a rash. While not everyone with mono will develop a rash, some individuals do experience skin rashes as a secondary symptom.

If you believe you’re experiencing symptoms of mono, you should seek immediate medical care. At AFC Urgent Care Cortez, our walk-in urgent care clinic is available 7 days a week for mono diagnosis and treatment in Cortez, CO. Simply walk into the clinic when it’s convenient, or pre-register in advance online.

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What is Mono and How Does it Spread?

Mononucleosis, often called "mono," is a viral infection most commonly caused by the Epstein-Barr virus (EBV). It primarily affects teenagers and young adults, but can occur at any age. Mono is sometimes referred to as the "kissing disease" because it is spread through saliva, though it can also be transmitted through other bodily fluids, such as blood or semen. It can also be transmitted by sharing utensils or close contact with an infected person.

Common Symptoms of Mono

Mononucleosis symptoms can vary in severity. Mono has a long incubation period of 4 to 6 weeks. This means that symptoms may not appear for up to 6 weeks after exposure, however, you can still be contagious before you start experiencing symptoms. One symptom that is unique to cases of mono is an aggressive rash that begins around the face and chest.

Common symptoms of mono include:

  • Fatigue
  • Sore throat
  • Fever
  • Swollen lymph nodes
  • Enlarged spleen or liver
  • Rash
  • Headaches and muscle aches
  • Loss of appetite

Potential Complications with Mono

While most cases of mononucleosis resolve on their own with rest and supportive care, the infection can sometimes lead to complications. Though rare, these complications can be serious and may include:

Enlarged spleen (Splenomegaly): One of the most common complications, an enlarged spleen can be at risk of rupture, which can cause severe abdominal pain and internal bleeding. If you have mono, it's essential to avoid contact sports or any activity that could increase the risk of spleen injury.

Liver issues: Some individuals with mono may develop hepatitis or inflammation of the liver. This condition can cause jaundice (yellowing of the skin and eyes), discomfort, and elevated liver enzymes. In severe cases, it may require medical attention.

Secondary bacterial infections: Because mono weakens the immune system, individuals with the disease are more susceptible to bacterial infections, such as strep throat or sinus

Anemia: In some rare cases, mono can lead to a decrease in red blood cells (anemia), which can cause fatigue, weakness, and dizziness.

Chronic fatigue syndrome: In some cases, people who have had mono report ongoing fatigue for months after recovery. This prolonged fatigue can sometimes be linked to the development of chronic fatigue syndrome.

Visit AFC Cortez for Same-Day Mono Diagnosis & Treatment

Mono is a common condition that is severely contagious and can cause complications in severe cases. If you’re experiencing symptoms of mono, AFC Urgent Care Cortez is here to help. Our clinic is fully equipped with a laboratory on-site for rapid diagnostic testing at the time of your visit. We’re open 7 days a week and never require you to schedule an appointment; simply walk into the clinic.

Our board-certified medical providers are trained to expertly identify signs of mono and treat them effectively. We work with most medical insurance plans and offer affordable care for self-paying patients. Simply walk into the clinic today, or give us a call to learn more at (970) 516-5500.

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